Which condition is most commonly associated with the formation of an abdominal aortic aneurysm?

Atherosclerosis is recognized as the primary condition linked to the formation of abdominal aortic aneurysms (AAAs). This degenerative disease, characterized by the buildup of plaques within the arterial walls, leads to the weakening and dilation of those walls. As the aortic wall becomes increasingly compromised, the risk of aneurysm formation escalates significantly.

The role of atherosclerosis in AAA development can be attributed to its impact on blood vessels, which includes inflammation, accumulation of lipids, and calcification. These processes contribute to the structural changes in the aortic wall, ultimately making it prone to rupture should an aneurysm develop.

While hypertension does play a role in vascular health and can contribute to the risk of other cardiovascular conditions, its relationship with AAAs is not as direct or significant as that of atherosclerosis. Venous obstruction and congenital heart defects are less relevant, as they do not have a primary association with the mechanisms leading to abdominal aortic aneurysm formation.